Welcome to the OBR Oncology Pipeline Online™

We strive to provide the most comprehensive and up to date oncology pipeline information resource that is widely available on the web. Explore the current state of the entire oncology pipeline by selecting a tumor type below. Alternatively, select one of the tabs below to search by category or use the main search box to customize your own search. Send us your feedback at editor@oncbiz.com.

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Acute Lymphoblastic Leukemia (ALL)1330
Acute Myelogenous Leukemia (AML)29107
Basal Cell Carcinoma (BCC)0420
Bladder4132
Bone Loss2215
Brain Metastases0022
Breast13156126
Cervical1201
Chronic Lymphocytic Leukemia (CLL)11046
Chronic Myelogenous Leukemia (CML)1323
Colorectal8162218
Endocrine0043
Endometrial0060
Esophageal0130
Gastric01103
Gastrointestinal Stromal Tumor (GIST)0247
Germ Cell0010
Glioblastoma Multiforme (GBM)14136
Glioma3574
Head & Neck26157
Hepatocellular carcinoma (HCC)12117
Hodgkin's Lymphoma0620
Leukemia0310
Lung2000
Melanoma8121914
Mesothelioma0121
Myelodysplastic Syndrome (MDS)05123
Myeloma114116
Myeloproliferative disorders0240
Non Small Cell Lung Cancer (NSCLC)5235928
Non-Hodgkin's Lymphoma (NHL)5292610
Ovarian692511
Pancreatic411217
Pediatric0243
Prostate9121815
Renal36169
Sarcoma02107
Small Cell Lung Cancer (SCLC)0652
Supportive Care2473
Thyroid0063
Uterine0010
Abbott Laboratories0580ABT
Abraxis BioScience Inc.2153ABII
Acceleron Pharma, Inc.1110Acceleron
Access Pharmaceuticals, Inc.1310ACCP.OB
Adherex Technologies Inc.0121ADHXF.PK
Advaxis Incorporated2100ADXS.OB
Adventrx Pharmaceuticals Inc.0200ANX
Affymax Inc.0010AFFY
Agios Pharmaceuticals Inc. 3000Agios
Allos Therapeutics Inc.0530ALTH
Ambit Biosciences4200Ambit
Amgen Inc.04149AMGN
Anadys Pharmaceuticals Inc.0100ANDS
Antigenics Inc.2622AGEN
Antisense Pharma GmbH 2301Antisense
Antisoma0364Antis
Aposense Ltd.0010Aposense
Apthera, Inc.0101Apthe
Argos Therapeutics, Inc.0100Argos
ARIAD Pharmaceuticals Inc.4331ARIA
Arno Therapeutics, Inc.1220Arno
ArQule Inc.5060ARQL
Array BioPharma Inc.0410ARRY
Ascenta Therapeutics2550Ascenta
AstraZeneca plc0685AZN
AVEO Pharmaceuticals Inc.1601AVEO
Bayer Healthcare05146Bayer
BioCryst Pharmaceuticals Inc.0120BCRX
Biogen Idec Inc.1333BIIB
BioNumerik Pharmaceuticals, Inc.0452Bion
Biovest International, Inc.0011BVTI.PK
BioVex Inc.0202Biov
BiPar Sciences, Inc.0072bipar
Boehringer Ingelheim Corporation0012Boehringer
Bristol-Myers Squibb Co.2161915BMY
Callisto Pharmaceuticals Inc.0310CLSP.OB
CEL-SCI Corporation0001CVM
Celator Pharmaceuticals0110Cela
Celgene Corporation0377CELG
Cell Genesys Inc.1120CEGE
Cell Therapeutics Inc.2023CTIC
Celldex Therapeutics, Inc.0210CLDX
Celsion Corporation0011CLSN
Centocor Ortho Biotech Products, L.P.0001Centocor
Cephalon Inc.2221CEPH
Champions Biotechnology, Inc.3000Champ
ChemGenex Pharmaceuticals Ltd.1060CXSP
Clavis Pharma ASA1220Clavis
Concordia Pharmaceuticals, Inc.0210Concordia
Cornerstone Pharmaceuticals Inc.1500Corner
Cougar Biotechnology Inc.2210CGRB
CuraGen Corporation3020CRGN
Curis Inc.1430CRIS
Cyclacel Pharmaceuticals Inc.0250CYCC
Cytokinetics Inc.0610CYTK
CytRx Corporation 0740CYTR
Delcath Systems, Inc.0011DCTH
Dendreon Corporation3300DNDN
Dyax Corporation2000DYAX
Eisai Inc.2661Eisai
Eli Lilly & Co.8978LLY
EMD Serono, Inc. 0665EMD Serono
Endocyte, Inc.3440Endocyte
EntreMed Inc.0650ENMD
Enzon Pharmaceuticals Inc.2510ENZN
Epeius Biotechnologies Corporation0200Epeius
EpiCept Corporation4111EPCT
Esperance Pharmaceuticals0100Esperance
Exelixis Inc.11651EXEL
Facet Biotech Corporation0130FACT
Five Prime Therapeutics, Inc.1100Five
Gemin X Pharmaceuticals0640Gemin
Genentech Inc. / Roche 0242931DNA
Generex Biotechnology Corporation1310GNBT
Genmab, Inc.2572Genmab
Genomic Health Inc.5000GHDX
Genta Incorporated0122GETA.OB
GenVec Inc.0211GNVC
Genzyme Corporation7131GENZ
Geron Corporation1120GERN
GlaxoSmithKline plc05138GSK
GlobeImmune, Inc.2030Globe
Gloucester Pharmaceuticals, Inc.0220Glou
GPC Biotech AG2222GPCB
GTX Inc.0112GTXI
Hana Biosciences Inc.0620HNAB.OB
Human Genome Sciences Inc.1120HGSI
Idera Pharmaceuticals Inc.0310IDRA
ImmunoCellular Therapeutics, Ltd.2210IMUC.OB
ImmunoGen Inc.3941IMGN
Immunomedics Inc.0640IMMU
Incyte Corporation0050INCY
Infinity Pharmaceuticals Inc.1330INFI
Inovio Biomedical Corporation1801INO
IRX Therapeutics2010IRX
Jennerex Biotherapeutics Inc.1220Jenn
Keryx Biopharmaceuticals Inc.0140KERX
Light Sciences Oncology0012Light
Medivation, Inc.0001MDVN
Memgen0100Memgen
Merck & Co. Inc.0961MRK
Merrion Pharmaceuticals, LLC0110Merrion
MethylGene Incorporated1000MethylGene
Micromet Inc.2420MITI
Millennium: The Takeda Oncology Company0782MLNM
Molecular Insight Pharmaceuticals Inc.0220MIPI
Monogram BioSciences Inc.4000MGRM
Myriad Genetics Inc.1220MYGN
Nektar Therapeutics0230NKTR
Neogenix Oncology Corporation0200Neogenix
NeoPharm Inc.1031NEOL.PK
Neotropix, Inc.0100Neo
Nereus Pharmaceuticals, Inc.0310Nereus
Northwest Biotherapeutics Inc.4211NWBO.OB
Novartis AG014910NVS
NovaRx Corporation0101Novarx
Novelos Therapeutics Inc.0020NVLT.OB
Novogen Inc.4023Novo
OncoGenex Pharmaceuticals, Inc.2221OGXI
Oncolytics Biotech Inc.0350ONCY
OncoMed Pharmaceuticals, Inc.0100Onco
Onconova Therapeutics Inc.1210Oncon
Oncothyreon Inc.0212ONTY
Oncovista Innovative Therapies Inc.1120OVIT.OB
Onyx Pharmaceuticals Inc.12105ONXX
Orion Genomics5000Orion
OSI Pharmaceuticals Inc.0313OSIP
OXiGENE Inc.0121OXGN
PDS Biotechnology Corporation3000PDSBio
Peregrine Pharmaceuticals Inc.0140PPHM
Pfizer Inc.0153916PFE
Pharmacyclics Inc.1220PCYC
Plexxikon Inc.1101Plexxikon
Poniard Pharmaceuticals Inc.0121PARD
Predictive Biosciences9000Pred
Progen Pharmaceuticals Ltd.1100PGLA
Progenics Pharmaceuticals Inc.2000PGNX
Provectus Pharmaceuticals, Inc.0010PVCT.OB
Raven Biotechnologies, Inc.9100Raven
Regeneron Pharmaceuticals Inc.0013REGN
Rexahn Pharmaceuticals, Inc.1020RNN
S*BIO Incorporated2300Sbio
sanofi-aventis410313SNY
Schering-Plough Corporation0066SGP
SciClone Pharmaceuticals Inc.0011SCLN
Seattle Genetics Inc.2820SGEN
Semafore Pharmaceuticals2200Sema
Spectrum Pharmaceuticals Inc.1331SPPI
Sunesis Pharmaceuticals Inc.0311SNSS
SuperGen Inc.3400SUPG
Syndax Pharmaceuticals, Inc.0550Synd
Synta Pharmaceuticals Corporation1270SNTA
Tamir Biotechnology, Inc.3101ACEL.PK
Telik Inc.8040TELK
Threshold Pharmaceuticals Inc.0310THLD
Tigris Pharmaceuticals, Inc.2100Tigris
Tokai Pharmaceuticals, Inc.0100Tokai
TRACON Pharmaceuticals, Inc.1300Traco
Transmolecular, Inc.0220Trans
Trubion Pharmaceuticals Inc.1100TRBN
Vermillion Pharmaceuticals Inc.3000VRML.OB
Vical Incorporated0101VICL
Xencor, Inc.2100Xencor
YM BioSciences Inc.00113YMI
ZIOPHARM Oncology Inc.0232ZIOP
ZymoGenetics Inc.0120ZGEN
?2-integrin expression inhibitor0100
ABL kinase inhibitor1000
activin inhibitor0100
ActRIIA inhibitor0010
ActRIIB inhibitor0100
AKT inhibitor0260
ALK inhibitor3000
ALK inhibitor (oral)0201
ALK1 inhibitor1000
alkaloid (oral)0100
alkylating agent01611
alkylating agent potentiator1000
alkylator-glucose conjugate0010
alpha-emitting radiopharmaceutical0011
altered energy metabolism-directed (AEMD) compound1500
analog of calcitriol0100
analog of dolastatin 151010
androgen receptor antagonist0200
antagonist of IAP's0100
anthracycline0201
anthracycline (doxorubicin prodrug)0300
anthracycline antiobiotic0001
anti-alpha4-integrin monoclonal antibody (humanized)0100
anti-cancer stem cell antibody0100
anti-CD137 monoclonal antibody1100
anti-CD19 monoclonal antibody (humanized)1100
anti-CD19 monoclonal antibody (maytansin-loaded)0100
anti-CD19 monoclonal antibody (surface antigen specific for B cells)0110
anti-CD20 monoclonal antibody0304
anti-CD20 monoclonal antibody (humanized)0462
anti-CD20 small antibody0100
anti-CD22 monoclonal antibody0030
anti-CD23 monoclonal antibody0010
anti-CD30 monoclonal antibody (humanized) 0100
anti-CD30 monoclonal antibody (humanized, non-fucosylated)0100
anti-CD32 monoclonal antibody (humanized)1000
anti-CD33 monoclonal antibody (humanized)0200
anti-CD33 monoclonal antibody (maytansin-loaded)0100
anti-CD37 small antibody1000
anti-CD38 monoclonal antibody (humanized)0100
anti-CD38 monoclonal antibody (naked)0200
anti-CD40 monoclonal antibody (humanized)1720
anti-CD70 monoclonal antibody1000
anti-CD70 monoclonal antibody (humanized)0200
anti-CD74 monoclonal antibody0300
anti-CD80 monoclonal antibody0001
anti-CEA monoclonal antibody (humanized)0010
anti-chemokine receptor (CXCR4) monoclonal antibody1000
anti-CS1 monoclonal antibody (humanized)0020
anti-CTLA4 monoclonal antibody (humanized)0083
anti-DKK1 monoclonal antibody0100
anti-DR5 monoclonal antibody0100
anti-DS6 monoclonal antibody (maytansin-loaded)1000
anti-EGFR monoclonal antibody0037
anti-EGFR monoclonal antibody (humanized)02128
anti-EpCAM monoclonal antibody0020
anti-hepatocyte growth factor (HGF) monoclonal antibody0100
anti-hepatocyte growth factor/scatter factor (HGF/SF) monoclonal antibody0010
anti-human epidermal growth factor receptor 3 (HER3) monoclonal antibody0100
anti-IGF-1R monoclonal antibody0210
anti-IGF-1R monoclonal antibody (humanized)0110
anti-mitotic kinesin centromere-associated protein E (CENP-E)0100
anti-MUC1 monoclonal antibody (humanized)0010
anti-nicotinamide phosphoribosyl transferase (NAMPRT)0200
anti-NRP1 monoclonal antibody0100
anti-PD-L1 monoclonal antibody (humanized)0100
anti-PD1 monoclonal antibody (humanized)0100
anti-phospholipid monoclonal antibody0130
anti-platelet derived growth factor receptor alpha (PDGFR(alpha)) monoclonal antibody (humanized)0300
anti-PlGF monoclonal antibody0100
anti-PSCA monoclonal antibody (humanized)0100
anti-receptor activator of nuclear factor kappa B ligand (RANKL) monoclonal antibody0004
anti-Ron monoclonal antibody1000
anti-Tie-1 monoclonal antibody (humanized)1000
anti-tissue factor monoclonal antibody (humanized)1000
anti-TRAIL receptors 1 and 2 monoclonal antibody0020
anti-TRP-1 monoclonal antibody1000
anti-TWEAK (tumor necrosis factor-like weak inducer of apoptosis) receptor monoclonal antibody (humanized)0100
anti-vascular endothelial growth factor receptors 1, 2 and 3 (VEGFR 1-3) (oral)0011
anti-VE-cadherin monoclonal antibody1000
anti-VEGF monoclonal antibody00418
anti-VEGFR-1 monoclonal antibody (humanized)0200
anti-VEGFR-2 monoclonal antibody0032
anti-VEGFR-3 monoclonal antibody1000
antibody drug conjugate4284
antibody drug conjugate (ADC)0100
antibody drug conjugate (anti-CD22 monoclonal antibody linked to CalichDMH - humanized)0020
antibody drug conjugate (anti-CD30)0210
antibody drug conjugate (TAP compound)3800
antibody to TRAIL receptor 20100
antibody-cytokine fusion protein0200
antifolate0330
antimetabolite1231
antimetabolite (a folic acid antagonist)0010
antimetabolite (cytidine analog)0101
antimetabolite (cytidine analog) (oral)0100
antimetabolite (oral)0032
antimetabolite (oral)/cyclin-dependent kinase inhibitor (oral)0100
antimetabolite (pyrimidine analog)0100
antimitotic agent0400
antimitotic agent (oral)0100
antisense oligonucleotide2401
antitumoral agent0100
apoptosis inducer5110
apoptosis inducer (caspase activator)1000
aromatase inhibitor0001
aurora A kinase inhibitor1210
aurora kinase inhibitor1420
aurora kinase/VEGFR2 inhibitor1100
aurora kinases A, B, and C inhibitor0200
B-RAF kinase inhibitor2100
Bcl-2 inhibitor1612
Bcr-Abl and Lyn-kinase inhibitor0030
Bcr-Abl inhibitor1000
bisphosphonate0003
bisphosphonate (oral)0010
blood cell production stimulator0020
BRAF-selective kinase inhibitor 0101
c-Kit/VEGFR-2 inhibitor0100
c-Met inhibitor 0100
c-Met inhibitor (monovalent antibody)0110
c-Met kinase inhibitor0360
camptothecin analogue0120
cancer antigen vaccine0010
cancer metabolism3000
cancer stem cell antigen vaccine0200
cathepsin K inhibitor0010
Cdc7 inhibitor0100
Cdc7 kinase inhibitor0100
cell cycle inhibitor1360
centromere-associated protein E (CENP-E) inhibitor1100
chemoprotective agent0131
chemotherapeutic conjugate2000
chemotherapeutic conjugate (epothilone)0100
chemotherapeutic conjugate (microtubule inhibitor)0100
chemotherapeutic conjugate (vinca alkaloid)0130
chimeric monoclonal antibody (IgG1 class)0100
chimeric monoclonal antibody (inhibits a5ß1 integrin)0030
chimeric monoclonal antibody (inhibits CD105 - humanized)0200
CHK1 kinase inhibitor0100
clusterin inhibitor0021
combiplex technology platform: cytarabine-daunorubicin0100
combiplex techonology platform: irinotecan HCI-floxuridine0010
conditioned cell immunization antibody1000
copoisonerase inhibitor0100
cyclin D1 inhibitor0100
cyclin-dependent kinase inhibitor1401
cyclin-dependent kinase inhibitor (oral)0020
death receptors DR4 and DR5 inhibitor0010
dendritic cell activator0110
dendritic cell activator (DCA)0111
diagnostics12000
dinuclear-platinum complex1000
DNA aptamer0020
DNA methyltransferase inhibitor2000
DNA minor groove binding agent (synthetic)0010
DNA vaccine0500
doxorubicin enhanced with lysolipid thermally sensitive liposomes (LTSL)0011
DPD inhibitor0010
DR5-targeted pro-apoptotic receptor agonist (PARA)0120
drug delivery platform 0011
dual pro-apoptotic receptor agonist which activates DR4 & DR5 / VEGF inhibitor0120
dual Src/Abl tyrosine kinase inhibitor0011
E2F1 pathway activator1030
Eg5 inhibitor1000
EGFR inhibitor1132
EGFR tyrosine kinase inhibitor0101
EGFR/HER2 inhibitor0001
EGFR/HER2 inhibitor (oral)0100
electroporation therapy0101
endogenous peptide0010
endothelin A receptor antagonist0001
endothelin B receptor agonist0100
EpCAM (CD326) antibody1210
epigenetic abnormality blood test1000
epigenetic modulator1000
epothilone1162
epothilone (fully synthetic) 0010
ErbB kinase inhibitor0100
ErbB-2 and EGFR dual kinase inhibitor0123
ErbB-2 inhibitor0100
ErbB/VEGF receptor inhibitor0100
ErbB1 and ErbB2 inhibitor0221
factor VIIa inhibitor0100
Fc-peptide fusion protein targeting angiopoietins (peptibody)0030
fibroblast growth factor receptor 1 (FGFR1) antagonist1100
Flt-3 kinase inhibitor0110
Flt-3 mononclonal antibody2000
Flt-3, PDGFR and c-KIT inhibitor0010
fluoropyrimidine (oral)0007
FMS kinase inhibitor1000
focal adhesion kinase (FAK) inhibitor0100
gene targeted drug using Argent system2000
gene therapy vector0200
glucose analog (synthetic)0100
glutathione S-transferase P1-1 (GST P1-1) agonist0020
GnRH antagonist (oral)0100
halichondrin B analog (synthetic)0030
HDAC inhibitor21080
HDAC/EGFR/HER2 inhibitor0100
HDAC/PI3K/mTOR inhibitor1000
HDM2-p53 inhibitor (oral)1000
hedgehog pathway inhibitor0670
hedgehog pathway inhibitor (oral)0010
hemiasterlin analog (synthetic)0100
heparanase inhibitor1000
HER dimerization inhibitor0031
HER1/EGFR inhibitor0026
HGF/c-Met pathway inhibitor1000
HIF-1 inhibitor2100
high-affinity monoclonal antibody8000
highly lipophilic camptothecin0241
histamine H2 receptor agonist0001
Hsp27 inhibitor0100
Hsp90 inhibitor48151
hypocalcemic agent0100
hypoxia-activated prodrug (HAP)0200
IAP inhibitor1000
ifosfamide metabolite0002
IgG1 monoclonal antibody2320
IgG1 monoclonal antibody (humanized)0211
IgM monoclonal antibody (humanized)1000
IL-34 antagonist1000
imaging agent1020
imaging agent (for detection of prostate-specific membrane antigen (PSMA))0100
immune system modulator0064
immunosuppressive0010
immunotherapy14251311
immunotherapy (nanoparticle)3000
immunotherapy (peptide-based)0101
immunotherapy (RNA-loaded DC) 0100
immunotherapy (stimulant of the TH1-specific cellular immune system)1010
immunotherapy (synthetic vaccine)0010
immunotherapy (targeting EGFRvIII)0010
immunotherapy (targets cancers expressing HER2 and/or CEA)0100
immunotherapy (WT1 heteroclitic peptide)0400
inhibitor of inosine monophosphate dehydrogenase (IMPDH) (oral)0110
inhibitor of the steroidal enzyme 17 alpha-hydroxylase/C17,20 lyase (oral)0010
insulin-like growth factor-1 receptor (IGF-1R) inhibitor (humanized monoclonal antibody)0010
insulin-like growth factor-1 receptor (IGF-1R) inhibitor (IGFBP-2 and IGFBP-5 inhibitor)1000
insulin-like growth factor-1 receptor (IGF-1R) inhibitor (monoclonal antibody)05130
insulin-like growth factor-1 receptor (IGF-1R) tyrosine kinase inhibitor (oral small molecule)0100
integrin inhibitor0021
interleukin-13 (IL-13) and PE38 recombinant protein 0001
JAK inhibitor2130
JAK2 inhibitor1200
kinase inhibitor1000
KIT, PDGF and VEGF inhibitor0200
KSP inhibitor0610
L-nucleoside conjugate1000
LH inhibitor (oral)0100
light activated drug treatment0012
lipid suspension of leteprinim1000
liposomal encapsulated c-raf antisense oligonucleotide1000
liposomal formulation of a potent thymidylate synthase (TS) inhibitor0020
liposomal formulation of docetaxel0020
liposomal formulation of paclitaxel0010
liposomal platinum agent0300
liposomal retinoic acid2000
liposomal topotecan0200
liposomal vincristine0020
liposomal vinorelbine0300
luteinizing hormone releasing hormone agonist0010
lysyl pro-drug of aminoflavone (AF)0100
macrophage activator0001
MAPK inhibitor0100
MDM2 antagonist0100
MEK inhibitor0320
MEK/PI3K inhibitor1000
membrane-disrupting peptide (MDP)0100
MET inhibitor (oral)0030
MET kinase inhibitor0200
microtubule inhibitor2085
mitotic inhibitor0010
MMP-14 protease inhibitor1000
modified herpes-simplex 1 virus injected directly into tumor0202
molecular screening test4000
monoclonal antibody1000
monoclonal antibody (diagnostic)1000
mTOR inhibitor0484
multi-IAP (oral)0100
multiple signal transduction regulator4023
multiple tyrosine kinase inhibitor3145723
multiple tyrosine kinase inhibitor (BCR-ABL and IGF1R and SRC0200
multiple tyrosine kinase inhibitor (CHK1 and CHK2)0100
multiple tyrosine kinase inhibitor (MET and RET)0242
multiple tyrosine kinase inhibitor (VEGF 1, 2, 3)0012
multiple tyrosine kinase inhibitor (VEGFR, FGFR, PDGFR)0001
multiple tyrosine kinase inhibitor (VEGFR-1, 2, 3, PDGFR, cKIT)0363
N-cadherin inhibitor0010
NAE inhibitor0200
neuropilin monoclonal antibody1000
neurotrophic0001
NK1 antagonist0001
non-polyglutamylatable antifolate0100
non-steroidal androgen synthesis inhibitor of the 17,20 lyase enzyme0010
notch signaling pathway inhibitor0100
nuclear export inhibitors (NEI)1000
nucleoside analog1110
oestrogen receptor antagonist0001
oncolytic poxvirus1220
oncolytic virus0550
onocyte-derived activated killer cell activator0010
organic arsenic0030
P-cadherin antagonist0100
p38/Tie-2 inhibitor0100
pan-Bcl-2 inhibitor (oral)1450
pan-DAC inhibitor0230
Pan-DAC/AKT pathway inhibitor1000
pan-HER inhibitor0211
pan-inhibitor of Bcl-2 proteins0440
pan-neutralizing IgG4 human antibody0100
PARP inhibitor01122
PEG recombinant alpha-2b interferon0001
PEG-L-asparaginase0200
PEGylated cytotoxic0110
pegylated peptide-based erythropoiesis-stimulating agent (ESA) (synthetic)0010
peptide-based targeted radiopharmaceutical (synthetic)0100
peptidomimetic inhibitor of geranylgeranyltransferase I (GGTase I) (synthetic)1000
PI3-k/AKT pathway inhibitor0100
PI3K and mTOR inhibitor0800
PI3K Inhibitor1800
PI3K inhibitor (oral)0100
PI3K/Akt/mTOR inhibitor0100
plasmid-based therapy1000
platinum chemotherapy agent0121
platinum chemotherapy agent (oral)0121
platinum prodrug0310
PLK-1 inhibitor0010
PNP inhibitor0120
polo-like kinase 1 (PLK1) inhibitor1100
polyamine analogue0100
polypeptide (synthetic)0220
pro-apoptotic TRAIL receptor-2 agonist0110
progesterone receptor antagonist0010
proteasome inhibitor1422
proteasome inhibitor (oral)0100
protein synthesis inhibitor0030
PTEN inhibitors & agonists1000
radiotherapeutic0110
Raf and VEGFR kinase inhibitor0100
Raf inhibitor1000
Raf kinase inhibitor0100
ras inhibitor0210
ribonuclease protein1101
ribonuclease technology platform2000
ribonucleotide reductase inhibitor0110
RNA antagonist (HIF-1 alpha antagonist)0200
RNA antagonist (LNA Targets)1000
RNA antagonist (Survivin Antagonist)1000
rose bengal disodium0010
selective androgen receptor modulator (SARM)0011
selective estrogen receptor modulator (SERM)0003
selective mitotic inhibitor0100
serine/therenine kinase inhibitor0001
serine/threonine kinase inhibitor0010
sheddase enzyme inhibitor0020
small molecule chemotherapeutic agent1200
SMO inhibitor0100
smoothened antagonist0100
somatostatin analog0011
SRC kinase inhibitor0010
supportive care0101
taxane0132
taxane (a synthetic retinoid) 0021
taxane (semi-synthetic)0012
telomerase inhibitor0110
test panel measuring HER receptor family members4000
thioredoxin reductase inhibitor0010
thrombopoietin agonist0140
thymidylate synthase inhibitor1000
TNFerade™ Biologic is an adenovector which contains TNF alpha for direct injection into tumors0211
toll-like receptor 7 agonist (TLR7) (prodrug)0100
toll-like receptor 9 (TLR9)0930
toll-like receptor 9 agonist (TLR9)0010
topoisomerase 1 inhibitor1130
topoisomerase 2 inhibitor0011
topoisomerase inhibitor1202
TORC1 and TORC2 inhibitor0100
tropomyocin receptor kinase A (TrkA) inhibitor1000
Trx-1 inhibitor0010
tumor associated antigen monoclonal antibody0200
tumor necrosis therapy (TNT)0010
tyrosine kinase inhibitor (Btk)1000
urine based diagnostic assay9000
vascular disrupting agent1384
VEGF inhibitor0110
VEGF receptors 1, 2 and 3 inhibitor0501
VEGF-A inhibitor0026
VEGF-R/Tie-2 kinase inhibitor0100
VEGF2 and EGFR tyrosine kinase inhibitor 0010
VEGFR and PDGFR inhibitor1000
VEGFR inhibitor1000
VEGFR-2 inhibitor0014
vinca alkaloid0100
yitrium-90 radiolabeled somatostatin peptide analog0010
yitrium-labeled antibody0100
18F-ML-100010
2-deoxyglucose0100
4613640100
6906930100
9232950100
abiraterone acetate0010
ABL (T3151)1000
Abraxane®0033
Abraxane® (+ Gemzar®)0010
ABT-2630600
ABT-86902100
AC 03-6361000
AC CJ-0011000
AC CJ-0021000
AC2200100
AC4800100
ACE-0110110
ACE-031 0100
ACE-0411000
Acyline0100
adecatumumab0020
adecatumumab (+ docetaxel)0100
ADH-10010
ADXS11-0010100
ADXS31-1421000
ADXS31-1641000
AE371310
Afinitor®0121
aflibercept0026
AFP-4640100
AGS-0030100
Alimta® 0010
alkeran0002
Allovectin-7®0001
Alocrest™0300
Alpharadin™0011
alvocidib0001
AME133v0100
AMG 1020010
AMG 2080100
AMG 3860020
AMG 386 (+ paclitaxel)0010
AMG 4790020
AMG 479 (+ gemcitabine)0010
AMG 8880100
AMG 9000100
amonafide malate0001
amrubicin0001
amrubicin (+ cisplatin)0010
ANA7730100
antifibronecitin0100
AP 110142000
AP19032000
AP245341200
apomab0120
Aptocine™0012
AR-120100
AR-421000
AR-670120
Archexin™ 0020
Aromasin®0001
Aroplatin™0300
ARQ 1970020
ARQ 197 (+ erlotinib)0010
ARQ 5010020
ARQ 501 (+ gemcitabine)0010
ARQ 6211000
ARQ 7611000
ARQ-250RP1000
ARQ-350RP1000
ARQ-700RP1000
ARRY-3800100
ARRY-5200100
ARRY-5430100
ARRY-6140100
Arzerra™0062
arzoxifene0001
AS14020010
AS14090200
AS14110020
AS7030260100
ASG-5ME0100
AT-1011420
AT-101 (+ taxotere) 0030
AT-406 0100
atiprimod0110
ATRA-IV2000
AUY9220100
AV-2991000
AV-4120100
Avastin®00418
AVE16420010
AVE80620001
AVE96330100
AVN9440100
AVN944 (+ gemcitabine)0010
axitinib0363
AZD05300010
AZD11520100
AZD47690100
AZD48770100
AZD6244 (ARRY-142886)0010
AZD6244 (ARRY-886)0010
AZD77620100
AZD8330 (ARRY-424704)0100
AZD89310100
Azedra™0010
Azixa™0030
bafetinib0030
bavituximab0130
Bexidem®0010
BEZ2350100
BGC 945 (ONX 0801)1000
BGT2260100
BHQ8800100
BI 67270010
BIIB0150200
BiovaxID™0011
BKM1200100
Bladder Cancer Screen Test1000
blinatumomab0110
BMS7534930100
bonefos0001
bosutinib0011
Brakiva™0200
Breast Cancer Screen Test1000
brentuximab vedotin0210
brivanib0014
brostallicin0010
BT-0620100
CA91000
cabazitaxel0001
carfilzomib0010
carfilzomib (+ lenalidomide)0001
CBP5010010
CDX-1100010
CDX-13070100
CDX-14010100
CEA1000
CEP-119810100
CEP-187700100
CEP-281222000
Ceplene®0001
CG00700100
cilengitide0021
cintredekin besudotox IL-130001
citoplurikin1010
Clolar®1011
Collidem®0100
Colorectal Cancer Genomic Signature Test1000
conatumumab0110
cordycepin0100
Cotara®0010
CP-4126 (IV)0100
CP-4126 (oral)0100
CP-42001000
CPI-6130100
CPI-613 Oral1000
CPI-6140100
CPI-6150100
CPI-6160100
CPI-6170100
CPX-10010
CPX-3510100
CR011-vcMMAE1020
CR014-vcMMAE2000
crinobulin0100
crizotinib0201
CSP-92221000
CT-36101000
CU-9061000
CUDC-1010100
CXCR41000
CXS-2991000
CYC1160100
cyclopamine0100
cyclopamine (+ gemcitabine)0010
dacetuzumab0620
dalotuzumab0100
darinaparsin0030
DCVax®3211
Debio 09320100
DI17E60010
DNA-MT1000
docetaxel emulsion0100
Doxil®0001
Drug Development1000
dulanermin0110
DX-22401000
DX-24001000
E70800100
E73890030
E78200100
E79740100
EC02250100
EC04821000
EC04890100
EC05311000
EC06521000
EC1450030
EC170100
EC200010
elacytarabine0020
elotuzumab0020
elsamitrucin0100
EMD 12048310100
EMD 12140630100
eniluracil0010
ENMD-11980100
ENMD-20760310
entinostat0550
enzastaurin0001
EOquin®0001
EP-1000100
EP1285042000
EP1921121000
EP21671000
epothilone-folate0100
epratuzumab0030
ER noscapine1000
Erbitux®0037
ERCC1/RRM11000
Fareston®0002
farletuzumab0111
Faslodex™0001
figitumumab0330
forodesine HCL0120
FP-10390100
FPT0691000
GA1010100
galiximab0001
GC10080100
GDC-04490460
gemcitabine prodrug0100
Genasense®0012
Gene Signature Test1000
GFB-2041000
GGTI-24181000
GI-30001000
GI-4000 Tarmogen0030
GI-62071000
Gleevec®0011
Glionix™0100
glufosfamide0010
GMX17770200
GRNVAC10010
GRNVAC21000
GSK-9232950100
GTx-7580100
GVAX vaccine1020
Hematide™0010
HER 1/2/3 total1000
HER 1:2 heterodimer1000
HER 2:3 heterodimer1000
HER 3:PI3K complex1000
Herceptin®0002
HGS10291000
HuMax-CD32b™1000
HuMax-CD38™0100
HuMax-TF™1000
Hycamtin®0001
ICT-1070010
ICT-1091000
ICT-1210200
ICT-691000
IDM-21010010
IL-120100
IL-20100
IL-2/EP0100
IMC-18F10200
IMC-3G30300
IMC-A120010
imetelstat0110
IMGN3880100
IMGN9010300
IMO-2055 (EMD 1201081) (+ cetuximab)0330
IMO-2055 (EMD 1201081) (+ cisplatin, fluorouracil and cetuximab)0300
IMO-2055 (EMD 1201081) (+ erlotinib and bevacizumab)0300
INCB184240030
INCB78390020
indibulin0200
iniparib0072
INNO-2060300
INNO-3050400
inotuzumab ozogamicin0020
interleukin 21 (IL-21)0010
interleukin 21 (IL-21) (+ ritiximub)0100
interleukin 21 (IL-21) (+ sorafenib)0010
Interval Monitoring Assay™3000
Intestinal Trefoil Factor (TFF3)0010
IPI-4930100
ipilimumab0043
Iressa®0001
IRX 4-61000
ISF350100
ispinesib0310
Ixempra™0021
Ixempra™ (+ Avastin®)0010
JX-5940120
JX-9290100
JX-9631000
Karenitecin®0241
KID24 (RAV18)2000
KOS-15840020
KOS-18031000
KOS-24641000
L-Annamycin0200
L19-Interleukin 20200
L19-TNFalpha0100
labetuzumab0010
lapuleucel-T0300
larotaxel0022
LBY1350100
LDE2250100
LE-DT0020
LE-rafAON1000
LEP-ETU0010
lestaurtinib0010
lexatumumab0100
lintuzumab0200
lonaprisan0010
LUCA31 (RAV19)1000
LUCA38 (RAV14)2000
Lucanix®0001
lucanthone0100
lucatumumab0100
lumiliximab0010
Lung Cancer Recurrence Assay1000
Lung Cancer Screen Test1000
mapatumumab0020
Marqibo®0020
MDAM0100
MDV31000001
MDX-11050100
MDX-1106 (ONO-4538)0100
MDX-13420100
MDX-14010100
MDX-14110200
MEDI-5610010
MEDI-561 (IPI-504)0010
Melanoma Genomic Signature Test1000
menadione topical lotion0100
Mepact®0001
MetMAb0110
MG915161000
MGCD01030100
MGCD2650110
midostaurine0001
milatuzumab0300
MK-04570010
MK-07520100
MK-08220010
MK-24610100
MK-47210100
MKC-10240
MLN49240200
MLN5180010
MLN80540100
MLN82370110
MLN97080100
MORAb-0041000
MORAb-0090120
MORAb-0281100
motesanib diphosphate0011
MP-4700300
MP-5291000
MPC-21300100
MPC-31000100
MPI-4438031000
MT1101100
MT228 (MORAb-028)1000
MT293 (D93/TRC093)0100
Multikine®0001
Multiplex Predictive1000
nab®-17AAG1000
nab®-54041000
nab®-docetaxel0010
nab®-rapamycin0100
NAC0100
necitumumab0002
neratinib0011
neratinib (+ paclitaxel)0200
neratinib (+ trastuzumab)0010
NeuVax™0101
Nexavar®00188
nimotuzumab00113
NKTR-1020030
NKTR-102 (+ 5-fluorouracil (5-FU))0100
NKTR-1050100
Non-radiolabeled TM6010100
noscapine0100
noscapine analogs1000
NOV-0020020
NPC-1C0200
NPI-00520200
Nplate™0030
NSCLC Genomic Signature Test1000
NTX-0100100
NV-1281000
NV-1291000
NV-1301000
NV-1431000
obatoclax0440
OGX-011/TV-10110020
OGX-011/TV-1011 (+ docetaxel)0001
OGX-2251000
OGX-4270100
olaparib0020
omacetaxine mepesuccinate0030
Omnitarg™0031
OMP-21M180100
ON 01910.Na0110
ON 0445801000
Onalta™0010
Oncaspar®0200
Onconase®0101
Oncophage®0322
OncoVEX GM-CSF0202
Onrigin™0122
ONX 09120100
ON 0131050100
Opaxio™0012
oral fludarabine0002
oral gallium compound0100
Orazol™0010
Orion Colorectal Cancer Risk Test1000
ortataxel0010
OSI-0270100
OSI-9060100
OSI-9300100
Ostarine™0010
Ovarian Cancer High-Risk Triage Test1000
Ovarian Cancer Prognosis Test1000
Ovarian Tumor Triage Test1000
OVI-1171000
OVI-2370020
OXi45030100
ozarelix0010
P20450100
panobinostat0130
panobinostat (+ lenalidomide)0100
patupilone0011
PCI-247810110
PCI-274830100
PCI-327651000
PD 3329910100
PD-03329910100
PDL1920100
PEG-SN38 (EZN-2208)0110
Pegintron™0001
perifosine0140
PF-002998040111
PF-005622710100
PF-35126760010
PF-37320100100
PG110470100
phenoxodiol0003
PI-5451000
PI3K1000
picoplatin0121
pixantrone0001
plinabulin0110
PLK-11000
PLX4032 0101
pomalidomide0020
pralatrexate0230
pralatrexate (+ gemcitabine)0100
Preclinical Evaluation1000
Preclinical Platform1000
Prolia™0004
ProLindac™ 0310
Promacta®0010
Prostate Cancer Genomic Signature Test1000
Prostate Cancer Screen Test1000
Prostate Specific Membrane Antigen (PSMA)0100
Prostate Specific Membrane Antigen (PSMA) Antibody1000
Prostate Specific Membrane Antigen (PSMA) Vaccines1000
PV-100010
PX-120010
PX-4780100
PX-8660100
Quinamed®0030
R15070260
R1507 (+ erlotinib)0010
R36160010
R71120100
R71590100
R72040100
R73340100
R73470100
Radiolabeled TM6010120
RAF2650100
ramucirumab0032
RAV X1000
RAV120100
Recentin™0012
regorafenib0020
Renal Cancer Genomic Signature Test1000
Reolysin®0350
retaspimycin0010
retaspimycin (+ docetaxel)0100
retaspimycin (+ trastuzumab)0010
Revlimid®0042
Rexin-G®0200
Rezonic™0001
RGB-2866381000
RGB-3440641000
RH10200
rhApo2L/TRAIL0020
ridaforolimus1262
Rituxan®0004
robatumumab0010
romidepsin0220
RP1010010
RX-0047-Nano1000
S-10003
Sagopilone (ZK-EPO)0010
salirasib0210
sapacitabine0030
sapacitabine (+ seliciclib)0100
SAR1031681000
SAR1328851000
SAR34190200
SAR5666584000
SAR5675301000
SAR6509840200
satraplatin0121
SB-7439210200
SB13541000
SB1518 (ONX 0803)0200
SB1578 (ONX 0805)1000
SB9390100
Selective Electrochemical Tumor Ablation (SECTA) + (bleomycin)0101
seliciclib0020
seocalcitol0100
SF11260200
SF26261000
SGI-1101000
SGI-12521000
SGI-17760100
SGN-19A1000
SGN-751000
SGX5230100
SN23100100
SNS-0320200
SNS-3140100
sodium thiosulfate (STS)0001
Solazed™0100
SOM2300011
SPI-16200100
SPI-2051000
Sprycel®0022
SSR2447380100
SSR972250100
STA-90900270
STA-95841000
Stimuvax®0004
Stratification Assay™3000
SU-0148130010
SU148130010
Survivin ASO0100
Sutent®01177
TAK-7000010
TAK-7010100
talactoferrin0101
talactoferrin (+ sunitinib)0010
tamibarotene (+ arsenic trioxide)0020
tanespimycin0010
tanespimycin (+ bortezomib)0001
tanespimycin (+ trastuzumab)0020
Tarceva®0026
tasidotin1010
Tasigna®0002
tasisulam 0010
Tavocept™0111
Taxotere®0001
Telcyta®0020
Telintra®0020
Temodar®0035
TES7 (RAV17)2000
tesetaxel0010
TH-3020200
Thalidomide Pharmion™0001
The Delcath system™0011
ThermoDox®0011
thiarabine1000
thymoglobulin0010
tivozanib0501
TKI2580200
TLK587471000
TNFerade™0211
TOK-0010100
Torisel®0001
totrombopag0100
Tovok®0001
trabedersen0301
trastuzumab-DM10262
TRC0930100
TRC1021000
TRC1050200
tremelimumab0040
Triage Monitoring Assay™3000
Triapine®0110
triphendiol0020
Trisenox®0001
Trofex™0100
Trp-p81000
TRU-0161100
Tykerb®0023
Tysabri®0100
Unnamed241730
Uvidem®0010
V9300400
vadimezan0042
vandetanib0010
Vargatef®0001
Vectibix®0014
VEGFR21000
Velcade®0011
veliparib0130
veltuzumab0200
Versamune™3000
VGX 1501000
VGX-31000100
Vidaza®0201
vinorelbine emulsion0100
volociximab0030
vosaroxin0011
Votrient™0121
Votrient™ (+ Tykerb®)0021
xaliproden0001
Xcytrin®0010
Xeloda®0004
XL0190100
XL1390100
XL1470400
XL1840242
XL2280200
XL2810100
XL4130100
XL5180100
XL7650600
XL8200200
XL8440100
XL8800060
XL8881000
XmAb®25130100
XmAb®54851000
XmAb®55741000
Y-hPAM40100
Zadaxin®0001
zalutumumab (+ chemo-radiation)0100
zalutumumab (+ radiotherapy)0101
zibotentan0001
Zometa® 0002
Zybrestat™0021
Zymafos™ 0002
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Perform a search to view results here.

Disclaimer: This is an informational database only. Having a product listed in this database in no way implies that the associated company or organization endorses or recommends the use of that product in development. For further information, we recommend contacting the associated company directly.

Furthermore, the information contained in this database was compiled directly from each company's website as well as through additional resources available on the web. While we attempt to ensure the accuracy of this database, the information provided is only as accurate as each company provides and makes available to the general public. We thank you for your understanding.





A number of companies are following in Dendreon's footsteps with personalized cancer vaccines in their pipelines.

Catch up on a recent Scientific American post providing an overview of this newer class of cancer therapies. Then dig deeper on the companies and cancer vaccines being developed for tumor types including metastatic melanoma, two different kinds of lymphoma, and Glioblastoma multiforme (GBM).

Read about Bristol-Myers Squibb's ipilimumab; Northwest Biotherapeutics' DCVax®; and Biovest's BiovaxID®. In addition there's a Bloomberg update on Merck KGaA's cancer vaccines Stimuvax® and VXM01.

Recent Oncology Pipeline News

Celldex Says Pfizer Ends Cancer Vaccine Deal; Shares Fall

(Reuters) September 3, 2010 - Celldex Therapeutics Inc said its partner Pfizer ended the deal to co-develop Celldex's cancer vaccine, its lead product, as the program was no longer a strategic priority for the drug giant.
read article »

Celgene Seeks to Stop Natco's Generic Revlimid

(Reuters) September 3, 2010 - Celgene Corp said it plans to file a complaint alleging infringement against India's Natco Pharma Ltd, which has submitted a request to the U.S. Food and Drug Administration for authorization to make and sell generic versions of Celgene's cancer drug Revlimid in the United States.
read article »

Read ALL News »


Competitive Intelligence Report

Clinical Trial Resource Window

Progression-free survival, or PFS, remains a contentious surrogate endpoint in oncology clinical trials according to a July 27th NCI Cancer Bulletin featured article on Avastin.

Recently an ODAC committee voted 12 to 1 against the drug's use in combination with chemotherapy as a first-line treatment for advanced breast cancer. Whether the FDA will decide to rescind bevacizumab's approval as a breast cancer treatment remains up in the air until this September 2010.

Read about the original trial that Avastin's accelerated approval was based on, get more information on two pivotal follow-up studies, plus Dr. Richard Pazdur, director of the FDA’s Office of Oncology Drug Products, offers his commentary here.

OBR Radar
Stay ahead of market moving oncology events and peer into the future of the oncology industry with the new OBR Radar.